Once sufficient data is generated for your campaign you would need
to determine the reasonable initial value you are willing to work
with. Don’t expect to reach your ROI with the first optimization
you do, optimization usually take 2 months in order to reach your
ROI goal. Based on the reasonable initial ROI value you can go through
the keywords/channel report, site report, and geographic report
and target/block all the keywords, channel and sites based on the
reasonable initial ROI value you are willing to work with. After
the campaign has been optimized with the initial ROI value let it
run for a few more days and determine another ROI value you are
willing to work with and optimize your campaign accordingly again.
Repeat this step until you’ve reach your ROI value.